Mouse monoclonal IgG, specific for an epitope mapping between a.a. 515-555 within an internal region of MBD4 of mouse origin. Antibody Target: MBD4
antibody targetdescription
MBD4 may function to mediate the biological consequences of the methylation signal. In addition, MBD4 has protein sequence similarity to bacterial DNA repair enzymes and thus may have some function in DNA repair. Further, MBD4 gene mutations are detected in tumors with primary microsatellite-instability (MSI), a form of genomic instability associated with defective DNA mismatch repair, and MBD4 gene meets 4 of 5 criteria of a bona fide MIS target gene. (provided by RefSeq)
antibody vendorid
sc-271530
antibody vendorname
Santa Cruz Biotechnology
antibody
MBD4_(SC-271530)
cell description
hepatocellular carcinoma
cell karyotype
cancer
cell lineage
endoderm
cell organism
human
cell sex
M
cell
HepG2
controlid
SL6019
datatype description
Chromatin IP Sequencing
datatype
ChipSeq
lab description
Myers - Hudson Alpha Institute for Biotechnology
lab
HudsonAlpha
labexpid
SL8132,SL7901
protocol description
Faster ChIP protocol & AMpure XP size selection for ChIP-seq (Myers)
Instrument model unknown. ("Illumina Genome Analyzer" specified by default). For more information, see http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=wgEncodeHaibTfbs